It was once thought of as a variant of Multiple Sclerosis (MS), and is still oftentimes misdiagnosed as MS. However, several factors differentiate it from MS: 1) it does not often involve the brain, especially early in the disease, 2) the severity of attacks is more robust as compared to MS, and 3) the pathophysiology differs from MS ??? whereas MS is thought to largely be a T-cell mediated diseas