It can occur in neurodegenerative disorders, such as Parkinson's disease, Huntington's and Alzheimer's disease, in stroke, in epilepsy, in multiple sclerosis, in amyotrophic lateral sclerosis, and in mental failures, such as schizophrenia and depression.http://www.ncbi.nlm.nih.gov/pubmed/17017544PREMENSTRUAL EXACERBATIONS AND LOW GABALow levels of GABA just prior to the onset of the menstrual cycl