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  • It plays a major role in the degradation of the invariant peptide chain associated with the major histocompatibility complex and thus affects antigen presentation.1, 2 Since antigen presentation is the key to immune response, Cathepsin S has been validated as an immunomodulatory target.3, 4 Cathepsin S is also involved in several pathologies including atherosclerosis, cancer, obesity and their ass
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