It is not known if bupropion hydrochloride extended-release tablets (SR) can harm your baby. are breastfeeding. especially cirrhosis of the liver. have liver problems, have kidney problems. have an eating disorder such as anorexia nervosa or bulimia. have had a head injury. have had a seizure (convulsion, fit). have a tumor in your nervous system (brain or spine). have had a heart attack, heart pr