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  • Studies have used VBM to evaluate neuropsychiatric disorders, such as Alzheimer disease, obsessive-compulsive disorder, panic disorder, and posttraumatic stress disorder, as well as developmental processes, such as age-related alterations in gray matter.28- 32 Furthermore, a study by Testa et al33 suggested that VBM detects hippocampal changes in Alzheimer disease with greater sensitivity than tra
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