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  • It is predominantly synthesized by hepatocytes.1,2 C-reactive protein is an acute-phase reactant that has traditionally been used as a serologic marker of acute and chronic inflammation.1,2 C-reactive protein is normally present in trace levels in serum, but increases rapidly and dramatically in response to proinflammatory cytokines, such as interleukin (IL)-1, IL-6, and tumor necrosis factor.1???
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