Other objects of the invention relate to identification, detection and treatment of age related diseases including cancers (especially non-hereditary cancers) and neurodegenerative diseases, such as Alzhemier's Disease (AD), Parkinson's Disease (PD), Down's syndrome, frontal lobe dementia (Pick's Disease), progressive supranuclear palsy (PSP), amyotrophic lateral sclerosis, Huntington's Disease, m