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  • Etanercept is currently used for the treatment of chronic inflammatory diseases such as rheumatoid arthritis and psoriasis [14] and is effective in neutralizing TNF-?? in animal models of traumatic brain injury [15], endotoxemia [16] and spinal cord injury [17], leading to improved outcomes.In order to elucidate the role of TNF-?? in toxic liver failure in mice, the protective effects of etanercep
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