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  • Specifically, men under age 65 with a history of 40 or more pack-years" (those who smoke a pack a day for 40 years or two packs a day for 20 years) of cigarette smoking face a 100 percent increased risk ??? or double the risk ??? of developing more aggressive forms of the disease as compared to nonsmokers, according to senior author Janet L. Stanford, Ph.D., and colleagues in Fred Hutchinson's Pu
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