absent or is selected from the group consisting essentially of hydrogen, hydroxy, lower alkoxy and lower acyloxy; R6 is a hydrogen or a halo; and a represents optional aromatic unsaturation of ring A of said steroid, or b, c, and d are each optional double bonds; e, f, g, h, i and j are each optional double bonds; and e may also form an expoxy ring with C16 and C17.