2-propylene glycol or an ether of formula R1???(???O???(CH2))x???OR2, wherein R1 is alkyl or tetrahydrofurfuryl, R2 is alkyl, tetrahydrofurfuryl, or hydrogen, and x is an integer of 1 to 6; and wherein the at least one cyclosporin, the surfactant component, and the polar lipid component are present in effective amounts relative to each other so that the composition, on contact with an aqueous phas