So how might excess sugar and high-carbohydrate diets lead to the formation of rogue cancer cells? ???In light of our and other???s research, we theorize that factors including a high glycemic load [resulting in excess glucose or sugar byproduct throughout the bloodstream] may stimulate the body???s production of insulin,??? Jeffrey Meyerhardt, M.D., M.P.H., of Dana-Farber, said.