None of the additional Dictyostelium Rho-related proteins belongs to any of the other well-defined subfamilies, like Cdc42, Rho, or Rnd.Dictyostelium amebas are equipped with a complex actin cytoskeleton that endows the cells with chemotactic and motile behavior comparable to that of leukocytes, and like macrophages and neutrophils, Dictyostelium is a professional phagocyte.