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  • The method according to claim 34, wherein the first cationic polyamine component has an endosome membrane disruption promoting component of the formula ???B???(CR1R2)j???C(R)3, wherein C(R)3 is absent, R1 and R2 are each hydrogen; j is 0 and B is a bridging group selected from the group consisting of (i), (ii), (iii) and (iv).
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