.sub.2).sub.g --SO.sub.2 --(CH.sub.2).sub.h -- where g=1-2 and h=1-2, ##STR93##where j is 1 or 2 and Z is an amino group, alkylamino group, or piperidylamino group; and B is a substituted or unsubstituted C1 to C6 alkyl group; W is a hydrogen or C(O)R where R is as defined above;and pharmaceutically acceptable salts, esters or hydrates thereof.14.