Experts estimate that around 24 to 30 out of 100 cases of kidney cancer are directly related to smoking.2Have a job that regularly exposes you to certain chemicals or minerals, such as asbestos, gasoline, and cadmium (used in manufacturing).Use too much pain medicine for a long time.Have certain inherited conditions, such as von Hippel-Lindau disease.What are the symptoms?Kidney cancer does not usu