Additionally solvents, detergents and other agents are used to stabilize the drug formulation. [0043] Pressurized metered dose inhalers, or pMDIs, are an additional class of aerosol dispensing devices. pMDI's package the compound in a canister under pressure with a solvent and propellant mixture, usually chlorofluorocarbons (CFC's,), or hydroflouroalkanes (HFA's).