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  • , R 3 is a (C 1 -C 3 )alkyl group that is substituted with a group such as OH or with an oxo group Examples of such groups include, but are not limited to, -C(CH 3 ) 2 OH and -C(-O)-CH 3 In some embodiments, R 3 is selected from -F, -Cl, -OH, OCH 3 , SCH 3 , OCH 2 CH 3 , OCHF 2 , OCF 3 , OCH 2 CF 3 , O cyclopropyl, CHF 2 , CF 3 , C(=0) CH 3 , CH(CH 3 ) 2 OH, or -CH 2 CH 3 In some such embodiments,
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