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  • CHD is also a major cause of disease burden in terms of disability-adjusted life years lost (DALY), accounting for 63 million DALYs worldwide in 2004 [68].In addition to age and gender, modifiable risk factors are important, especially lifestyle factors like smoking and a lack of physical activity and the medical diagnoses hypertension, diabetes mellitus, obesity, and dyslipoproteinaemia [71].
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