??? CA-MRSA CA-MRSA infections often begin as skin or soft tissue lesions, such as a boil or abscess and/or cellulitis, with patients frequently reporting a lesion that is red, swollen and painful.24 CA-MRSA should be suspected particularly if a patient reports, or presents with, a wound resembling a spider bite, since MRSA strains can cause painful lesions in the absence of previous skin trauma.1