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  • IL-17 producing CD4+ T helper (Th17) cells produce several cytokines, the most important being IL-17 or IL-17A, which activated multiple cell types to produce proinflammatory cytokines, chemokines, nitric oxide ...However, in other tissues, such as liver, IL-22 has been shown to counteract the destructive nature of the inflammatory response, thus playing a protective role [33].
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