n full menstruation, flushing due to menopause,diarrha,opiates& methadone detoxification, withdrawal from alcohol and benzodiazepines such as valium. be sure if you decided to use the trazadone or seraquil these 2 will entisify the clonidine & zanax its like a double wammy if you want to sleep this is the way to go! give it a day or two to kick in but i took a leave of absent from work so i would