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  • In some embodiments, an effective amount of a TLR agonist is an amount that is effective to reduce integrin ??v??6 mRNA and/or protein levels in lung tissue by at least about 10%, at least about 20%, at least about 25%, at least about 30%, at least about 40%, at least about 50%, at least about 60%, at least about 70%, at least about 80%, or at least about 90%, or more, compared to the level of int
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