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  • In preferred embodiments of the above first aspect of the invention, the conjugate is a tolerogenic conjugate capable of inducing tolerance in a human patient suffering from SLE composed of a heterogeneous oligonucleotide at least 8 and not more than 500 base pairs in length covalently bonded to a non-antigenic, soluble isologous protein molecule, the covalent bonding being such that the conformat
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