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  • In a preferred embodiment of the invention, the tracer is a fluorescent compound of low steric hindrance such as fluorescein, dansyl, chromophores of the IR type (Li-COR Inc., Lincoln Nebr., USA), cyanine derivatives such as Cy5 and Cy3 (Randolph J. B. et al., Nucleic Acids Res., 25(14), p. 2923???2929, 1997) and in particular the Cy5 derivatives or alternatively the tracer is a hapten of low ster
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