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  • In the base-case analysis, after the first year, all costs and outcomes were discounted at 3% per annum.16 The 1-time cost of the intervention was based on time-motion studies conducted in a random sample of patients in the trial.2 The case manager spent a median of 70 minutes per patient divided among 4 activities, including patient education, arranging for and interpreting BMD tests, providing p
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