Since EDCs interfere with the body???s homeostatic control and alter normal development and reproduction, this finding helps scientists better understand how chemicals, such as bisphenol A, affect humans.The authors used two estrogen receptor (ER) negative cell lines, HepG2 and HeLa, to analyze the effects of three groups of EDCs on the estrogenic ERE-mediated and AP1/Sp1-mediated responses of ERa