; Q is ???C???C???; and R4 is hydrogen or hydroxy, said method comprising the steps of: (a) reacting, in the presence of a palladium catalyst, a compound of formula XI: P???O???CH2???(CH2)n???QH???(XI) wherein P is a general protecting group, and n and Q are as previously described, with Ar2Y, wherein Ar2 is as previously defined and Y is a transmetalation group, to afford a compound represented b