isease.25,26 In the first study, MetS was associated with increases in adjusted relative risk for aortic valve calcium of 45% in women and 70% in men; there also was an association of an increased number of MetS features with increased AVC prevalence in both genders.22 In the second study, MetS was associated with a doubling in the rate of progression of aortic stenosis, and the 3???year event???f