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  • It also failed to stimulate B cells, even though the modified Tall-1 did bind to one of its target receptors, BCMA. ???The flap region is essential for the proper function of Tall-1 in cell cultures,??? said Dr. Shu. ???We believe this region is a good target for development of small molecule drugs against lupus, rheumatoid arthritis, and other disorders involving the immune system and B cells.
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