It took about 4 weeks (360,000IU Serrapeptase a day, 9000FU Nattokinase, 1.4 mill units lumbrokinase + 300mg Lugols Iodine + lots of supporting minerals + 1 tsp borax a day) and I, excuse the language, shat out a putrid lot of black slime when my diet is mainly eggs and greens so that was not something I ate.