those with acne break out more or worse. --The Splenda symbol does not have to be put on the front label of any food or hygeneic product (toothpastes, mouthwash, gum) so read all No sugar Sugar Free Diet ingredient labels, among others, if this is a concern.http://www.acne.org/...showtopic=55819Personally, because acne is an Inflammatory Skin Disease or a Symptom of an Inflammatory Disease.