A phase II trial investigating response to ima- tinib in patients with unresectable melanoma harboring Copyright ?? 2012 SciRes. OPEN ACCESS El F. Hinde et al. / Open Journal of Obstetrics and Gynecology 2 (2012) 279-282 Copyright ?? 2012 SciRes. 282 somatic alterations of c-KIT is currently ongoing at six institutions, including Memorial Sloan-Kettering Cancer Center.