Preferred glutamate-derived hydroxyphosphinyl derivatives include compounds having the following formula: ##STR3## where R is a C1 -C9 straight or branched chain alkyl or alkenyl group, C3 -C8 cycloalkyl, C3 or C5 cycloalkyl, C5 -C7 cycloalkenyl, Ar1, substituted or unsubstituted C1 alkyl having a carboxy, substituted or unsubstituted C3 -C9 alkyl having a carboxy, or substituted C2 alkyl having a