r makes up less than 60 mol % of the mixture, and [0026] (c) a non-ionic surfactant having a hydrophilic lipophilic balance (HLB) greater than 10. [0027] The present invention is partly based upon the discovery that the carrier medium as defined in (b) above represents a particularly good solvent medium for cyclosporins, and therefore it is possible to avoid co-solvents such as ethanol, propylene