Dr Rob Hicks Symptoms of heartburn during the night include waking up with a bitter taste in the mouth, a chronic cough, sore throat or fatigue.Here are 27 tips for night-time heartburn relief:12 food and drink tips for night-time heartburn reliefReduce heartburn risk by limiting acidic foods such as grapefruit, oranges, tomatoes or vinegar.Spicy foods giving you heartburn?