This mechanism may also be present in other regions of the GI tract or in other organs, such as bladder and uterus, where TREK channels regulate excitability of smooth muscle cells.FundingTop of pageAbstractIntroductionMaterials and methodsResultsDiscussionFundingDisclosureAuthor contributionReferencesSupporting InformationThis work was supported by NIH DK57236 to SMW and DK41315 to KMS and SMW.Di