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  • The proinflammatory acute phase response is an orchestrated cascade of events in response to tissue injury, infection, or inflammation.1- 4 Characteristic of the acute phase response is up-regulation of acute phase proteins and a concomitant decrease in constitutive hepatic protein levels.1- 10 Mediators of the acute phase response are proinflammatory cytokines, such as interleukin (IL) 1??, IL-6,
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