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| - The $1.8 million, or 18%, increase in research and development expenses for the three months ended March 31, 2012 compared to the three months ended March 31, 2011 included a $992,000 increase in personnel-related expenses, a $841,000 increase in allocated information technology, facilities and other costs, a $176,000 increase in stock-based compensation expense, and a $137,000 increase in other e
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