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  • The reaction is conducted at a temperature of about 40??? C. The reaction solution is then quenched with a quenching agent such as sodium bicarbonate, for example, at a temperature of less than 30??? C. to yield the intermediate compound of Formula (XI) as shown in Scheme 4. [0167] The intermediate compound of Formula (XI) is converted to the acylated derivative by an excess amount of an acyl dono
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