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| - The study, of 4,363 patients from 48 sites in 15 countries, found that, when adjusted for age, sex, disease activity and traditional risk factors such as lack of exercise, smoking, diabetes and high cholesterols levels, risk correlated strongly with the use of drugs to treat RA. Taking methotrexate, for just one year for example was found to be associated with an 18 percent reduction in risk of he
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