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  • When Y is OCH3 the compounds of general formula (I) of Scheme I can be conveniently demethylated as outlined in Scheme XIV. Thus, the reaction of compound (I) wherein Y is OCH3 with boron tribromide in an organic solvent, such as dichloromethane, yields the corresponding phenol of formula (I) wherein Y is OH, and A, B, D, E, G, X, R2 and R3 are as defined above and R1 is an heterocyclic moiety sel
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