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  • The substituents on B and D include hydroxy, amino, halogen such as chlorine, bromine, iodine; optionally substituted linear or branched (C1 -C2) alkyl, especially (C1 -C6) alkyl group such as methyl, hydroxymethyl, aminomethyl, methoxymethyl, trifluoromethyl, ethyl, isopropyl, hexyl etc.; (C3 -C6) cycloalkyl groups such as cyclopropyl, fluorocyclopropyl, cyclobutyl, cyclopentyl, fluorocyclopentyl
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