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  • Through Watson-Crick base pairing, miRNAs bind to complementary sequences of mRNAs and induce either degradation or translational silencing of the target mRNAs.41 It is interesting to note that miRNAs are also themselves epigenetically regulated at their promoter level, and target many genes that play important roles in such processes as cell cycle progression, apoptosis, and differentiation.42 A
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