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  • The method of inhibiting angiogenesis in collagen-induced arthritis which comprises administering to a mammal in need of treatment an angiogenesis inhibiting dose of a compound of the formula ##STR17## wherein R and R1 are individually H or CH2 R4, except that at least one of R and R1 must be other than H, wherein R4 is (C1 -C21)alkyl-R5, (C2 -C12)alkenyl, (C2 -C12)alkynyl, (C3 -C8)cycloalkyl, (C3
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