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  • The Triazaspiro Compounds wherein R1 is H, n is 0, and R2 is ???COOR3 (wherein R3 is defined above) can be prepared by reacting Compound A with Compound B wherein R2 is ???COOR3 (wherein R3 is defined above) and X is a leaving group such as a benzenesulfonate, 4-methylbenzenesulfonate, 4-bromobenzenesulfonate, 4-nitrobenzenesulfonate, methanesulfonate, trifluoromethanesulfonate, or halogen in the
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