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  • These cells are normally quiescent and are held in an undifferentiated state within their niche until they receive a signal to self-renew or differentiate.3 They reside in various tissue types including the bone marrow, brain, digestive system, skin, retina, muscles, pancreas, and liver.4Hematopoietic stem cells (HSC) are the most widely studied and characterized adult stem cells.5 They play an es
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