The method of claim 1, wherein said terminal-phosphate-labeled nucleotide is: wherein P is phosphate (PO3) and derivatives thereof; n is 2 or greater; Y is an oxygen or sulfur atom; B is a nitrogen-containing heterocyclic base; S is an acyclic moiety, carbocyclic moiety or sugar moiety; and L is an enzyme-activatable label containing a hydroxyl group, a sulfhydryl group or an amino group suitable