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  • The cells from mice transfected with soluble CD8 resulted in specific lysis of the target cells a factor of 4 times lower than T cells from control mice at an E:T ratio of 10:1.Preferably in gene therapy, the modified CD8 molecules of the present invention are administered such that they are expressed in the subject to be treated, for example in the form of a recombinant DNA molecule comprising a
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