The reaction of the peptide with the excess moieties on the capsular wall surface is preferably conducted by adding an aqueous suspension or solution of the peptide(s), e. g., avidin, streptavidin, lectin, antibody, and other proteins or fragments thereof, to a suspension of the microcapsules at a temperature of about 4?? to 40?? C, more preferably at about 10?? to 25?? C., more preferably in the